in-vivo-services

Core Capabilities

Custom Animal Model Development

Genetically Engineered Models

CRISPR/Cas9-edited rodents (mice, rats), rabbits, swine, and primates for gene overexpression, knockouts, or lineage tracing.

Disease-Specific Models

Cardiovascular (coronary stent testing), neurological (Alzheimer’s, Parkinson’s), oncology (PDX models), metabolic disorders, and infectious diseases.

Surgical Models

Ischemia-reperfusion, organ transplantation, and minimally invasive DSA/CT-guided interventions.

Animal Breeding

SPF-Grade Rodents

Mice, rats, guinea pigs, and rabbits under pathogen-free conditions.

Large Animal Facilities

Swine, dogs, primates, and sheep with species-specific housing and enrichment programs.

Custom Breeding

Transgenic lines, immunodeficient strains, and timed pregnancies.

Surgical & Imaging Platforms

Advanced Surgical Suites:

DSA Hybrid Operating Room: For interventional cardiology and neurovascular studies.
CT/MRI Imaging: Longitudinal tracking of disease progression (e.g., tumor growth, cardiovascular remodeling).

Laparoscopic & Microsurgery

Minimally invasive techniques for reduced postoperative complications.

Postoperative Care

Dedicated recovery units with 24/7 monitoring.

Behavioral & Phenotypic Analysis

Motor/Cognitive Testing

Rotarod, Morris water maze, open field, and elevated plus maze.

Emotional/Neurological Profiling

Forced swim test, tail suspension, social interaction assays.

Pain & Sensory Evaluation

Von Frey filaments, hot/cold plate tests.

Pharmacology & Toxicology Studies

Dose-Ranging & Efficacy

PK/PD modeling, biomarker quantification (LC-MS/MS, ELISA).

Safety Assessment

Acute/chronic toxicity, organ function panels (hematology, histopathology).

Why Partner with HuaTeng Biotechnology?

✅ Global Infrastructure:
10,000+㎡ facilities in Guangzhou, Shenzhen, Chongqing, and Hong Kong.
AAALAC-accredited animal centers with ISO 17025-certified labs.

✅ Regulatory Compliance:
Full compliance with FDA-GLP, OECD, and IACUC guidelines.
CMA-certified data reporting for global submissions.

✅ End-to-End Support:
Protocol design, model customization, data analysis, and publication/patent support.
Training programs for surgical techniques and animal handling.

Why Choose HuaTeng Biotechnology for GLP-Compliant Testing?

Trusted Quality. Global Compliance. Proven Execution.

Global Compliance: AAALAC-accredited facilities with IACUC oversight, aligned with EU Directive 2010/63/EU and USDA standards—ensuring full regulatory acceptance across major markets.

Advanced Imaging Capabilities: Integrated platforms including DSA, IVUS, angiography and micro-CT, enabling real-time evaluation of device performance and in vivo outcomes.

Custom Model Development: Species-specific animal models tailored to complex disease conditions, improving translational relevance and clinical predictability.

Integrated Histopathology Suite: SEM and TEM analysis supported by GLP-grade reporting, enabling seamless submission to PMDA, CE Mark and global regulatory authorities.

In Vivo