Preclinical Evaluation Services for Dermal Repair Devices

Industry-Standard Animal Models

Target Devices & Corresponding Models

Medical Device	Preferred Species	Disease Model
Synthetic Skin Substitutes	Porcine	Full-thickness excisional wound
Burn Dressings	Rabbit	Second-degree burn model, Third-degree burn model
Diabetic Ulcer Patches	db/db mouse	Hyperglycemic chronic wound
Scar Modulation Gels	Guinea Pig	Hypertrophic scar induction

Test Category	Methodology
Barrier Function	Transepidermal water loss (TEWL) measurement
Cellular Infiltration	Multiplex IHC (CD68+/CD163+ macrophages)
Mechanical Strength	Tensile testing (ASTM D882)
Anti-Microbial Activity	Zone of inhibition (ASTM E2149)