Target Devices & Corresponding Models
| Medical Device | Preferred Species | Disease Model |
|---|---|---|
| Synthetic Skin Substitutes | Porcine | Full-thickness excisional wound |
| Burn Dressings | Rabbit | Third-degree burn model |
| Diabetic Ulcer Patches | db/db mouse | Hyperglycemic chronic wound |
| Scar Modulation Gels | Guinea Pig | Hypertrophic scar induction |
| Test Category | Methodology |
|---|---|
| Barrier Function | Transepidermal water loss (TEWL) measurement |
| Cellular Infiltration | Multiplex IHC (CD68+/CD163+ macrophages) |
| Mechanical Strength | Tensile testing (ASTM D882) |
| Anti-Microbial Activity | Zone of inhibition (ASTM E2149) |