Preclinical Evaluation Services for Orthopedic Materials

Industry-Standard Animal Models

Target Devices & Corresponding Models

Medical Device	Preferred Species	Disease Model
Bone Cement	Ovine (Sheep)	Osteoporotic lumbar vertebrae
Artificial Joints	Caprine (Goat)	Femoral condyle defect
Spinal Fusion Cages	Porcine (Swine)	Intervertebral disc degeneration
Bone Plate/Screw Systems	Canine (Beagle)	Tibial osteotomy

Test Category	Methodology
Osseointegration	Histomorphometry (Bone-to-implant contact %)
Corrosion Resistance	SEM/EDS analysis of metal ion release
Dynamic Loading	5Hz cyclic compression (1000N, 10M cycles)
Wear Simulation	Hip joint simulator (ISO 14242-3 gait cycle)