Preclinical Evaluation Services for Dental Materials

Industry-Standard Animal Models

Target Devices & Corresponding Models

Medical Device	Preferred Species	Disease Model
Dental Implants	Canine (Beagle)	Mandibular bone defect
Bone Graft Materials	Porcine (Swine)	Alveolar ridge augmentation
Guided Tissue Regeneration (GTR) Membranes	Ovine (Sheep)	Periodontal defect
Orthodontic Screws	Rabbit (NZ White)	Maxillary expansion model

Test Category	Methodology
Osseointegration	Toluidine blue staining (BIC% quantification)
Degradation Profile	Mass loss tracking (TGA/DSC analysis)
Mechanical Stability	Reverse torque testing (Ncm)
Soft Tissue Integration	Histological scoring (Epithelial attachment)